FIP Research

FIP Research, Trials, and USDA Regulations (1).

As a distributor, VetImmune® does not run clinical trials. Because veterinarians and customers often ask questions about Polyprenyl Immunostimulant™ trials, we are listing past, current, and planned Sass & Sass, Inc. clinical studies and trials that involve Polyprenyl Immunostimulant™ (PI).

Feline Infections Peritonitis (FIP) – a generally fatal feline disease – was a research interest of Dr. A.M. Legendre of the University of Tennessee-Knoxville (UTK). In 2003, Dr. Legendre suggested trying PI for FIP. His collaboration with Sass & Sass, Inc., which started with feline rhinotracheitis, was then expanded to include FIP in 2006. Research on FIP was presented at the ACVIM Meeting in New Orleans in May 2012, and the AAHA Meeting in Phoenix, AZ  in 2013. Feline Infectious Peritonitis (FIP) is a devastating disease caused by a mutated form of feline coronavirus that triggers global immunity failure in a cat. FIP has long been considered an incurable, fatal disease. There are two main forms of FIP, effusive (wet) and non-effusive (dry). The way clinical FIP develops as an immune-mediated disease is unique, unlike any other viral disease of animals or humans. This interaction between the body’s own immune system and the virus is responsible for the disease. Once a cat develops clinical FIP involving one or more systems of the cat’s body, the disease is progressive and almost always fatal. The research focused on the most common non-effusive, “dry” form which exhibits a variety of pathologies, including pyogranulomatous infiltration in various organs. 


Sass & Sass, Inc. Polyprenyl Immunostimulant™ Research and Development timeline & benchmarks (FIP.)

(1) Results of research published in peer-reviewed journals cannot be used to substantiate health claims and do not substitute government regulated trials.

(2) Please note that under their ethics in clinical trials guidelines, Sass & Sass, Inc. believes that study animals should not be euthanized but should be provided a chance through adoption and be treated like any owned pet. Sass & Sass, Inc. does not purposely infect animals with fatal diseases and does not support any research that does.

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